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First In Human

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Just miles from the nation’s capital, on the campus of the revered National Institutes of Health, sits the Clinical Center, or Building 10: the largest hospital in the world devoted solely to medical research. The building houses the brilliant minds and courageous patients that enroll in “First in Human” clinical trials. Wading into uncharted medical territory in the hopes of discovering scientific breakthroughs, these early, highly experimental – and at times risky tests – are all in an effort to develop new, breakthrough treatments for patients suffering from currently untreatable diseases and conditions.


Narrated and executive produced by Emmy,® Golden Globe®, and Critics Choice® winning actor Jim Parsons (“The Big Bang Theory,”  “Hidden Figures,”) FIRST IN HUMAN is a three-part, six-hour medical documentary series taking viewers inside the crucial beginning phase of scientific research. The powerful series follows four diverse patients as they participate in a “First in Human” trial – the initial time when a new therapy is tested in humans, revealing the quiet heroism of both doctors and patients. If successful, the next chapter of medicine is written.  The series, directed by Emmy® winner John Hoffman and executive produced by Hoffman and Emmy® winner Dyllan McGee, begins airing August 10 at 9pm ET/PT exclusively on Discovery.